INNCELL -3D
Ready-to-Use, Self-Developing 3D Cell Culture Kit, Inserts, Instant Scaffold and Organ-on-a-Microplate System
INNCELL-3D is a proprietary, patented, ready-to-use, self-developing cell culture kit designed for creating 3-dimensional cell cultures. This innovative kit is ideal for various in vitro studies, microbial research, and virus research, and serves as an alternative to preclinical animal models.
Traditional preclinical animal model studies usually require a large number of animals, resulting in significant CO2 emissions from maintaining livestock and carcass bio-hazard incineration. However, we plan to reduce CO2 emissions and minimize bio-hazard waste, delivering human, animal, and environmentally safe products.
Comparison between 2D and 3D cell cultures
2D and 3D cell culture systems are used in biomedical research and drug development to study the behaviour and function of cells in vitro.
2D cell culture refers to the traditional method of growing cells on a flat surface, such as a plastic dish or flask. This system allows for easy visualization and manipulation of cells, as well as the study of basic cellular processes. However, 2D culture systems lack the complexity and physiological relevance of in vivo environments, limiting their ability to accurately represent tissue and organ function.
On the other hand, 3D cell culture systems aim to recreate the three-dimensional architecture and microenvironment of tissues or organs in vitro. 3D cell culture systems better mimic tissue physiology and enable the study of cell behaviour and responses more accurately. They allow for cell-cell and cell-matrix interactions, diffusion of nutrients and oxygen, and the formation of tissue-like structures. Additionally, 3D culture systems can be used to study diseases, drug screening, and tissue engineering applications.
Advantages of INNCELL -3D
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Ready-to-use, self-developing, and easy-to-use 3D cell culture kit that forms 3D structures at room temperature.
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Maintains a neutral pH, supporting optimal cell growth and adherence.
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Allows for the creation of various thicknesses suitable for different in vitro studies.
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Reduces the number of animals required for in vivo studies and shortens the preclinical study period.
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Biocompatible for use as an implant and in tissue transplantation with stem cells.
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Biocompatible and biodegradable.
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Can be molded into various tissues with specific cell lines for in vitro studies.
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Environmentally friendly and safe.
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Enables cruelty-free testing for drugs and cosmetics.
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Helps reduce environmental CO2 levels and bio hazardous waste.
Animal research and its global environmental impacts
Animal research and testing have several environmental impacts globally, including increased costs, pollution, and greenhouse gas emissions.
1. Increased Costs: Research involving animals is expensive due to the need for animal care, facilities, and specialized equipment. Costs rise further when specific animal breeds need to be acquired and transported.
2. Pollution: Animal research facilities produce waste like excrement, bedding, and carcasses. If not properly managed, this waste can contaminate water and soil, harming ecosystems.
3. Greenhouse Gas Emissions: Animal research contributes to greenhouse gas emissions primarily through energy use in running facilities—including lighting, heating, and air conditioning—as well as through the incineration of carcasses and the production and transportation of animal feed and bedding.
To mitigate these environmental impacts, some measures can be taken:
1. Reduction in animal use: Researchers can explore alternative methods to replace, refine, or reduce animal testing. This includes utilizing in vitro models, computer simulations, and 3D tissue cultures, among others. Incorporating these alternatives can help minimize the use of animals and consequently reduce associated environmental impacts.
2. Efficient resource management: Implementing sustainable practices in animal research facilities, such as energy-efficient lighting and equipment, proper waste management systems, and the use of environmentally friendly materials, can help reduce costs and minimize pollution generation.
Our innovative platform, INNCELL-3D minimizes animal use in testing and reduces these environmental impacts.
We offer 3D disease modeling services using our innovative INNCELL-3D tissue engineering platform technology, which serves as an alternative to preclinical animal studies for testing drugs, biologics, and cosmetics for safety, efficacy, and toxicity. We are developing a range of animal disease models for research purposes. For more details on the various disease models available for research, please visit our service page.